Capabilities
Precision-built assays. Integrated chemistry and biology. Mechanistic insights that truly move science forward
Why Work With Us?
Medicinal chemistry
Same-day compound synthesis and electrophysiology testing
Custom Electrophysiology
Fully taylored assays built around your target’s biology
Cellular & Organellar Expertise
From whole-cell patch clamp to lysosomal and mitochondrial channels
Integrated Chemistry and Biology, Same-Day Feedback
💡Design ⚗ ️Synthesize 🧪 Test Same Day
Chemistry and Biology work as one team. Our Electrophysiology lab is inside the chemistry lab, so every compound is tested immediately, giving same day feedback that drives precise, focused chemistry.
No wasted molecules only compounds worth making
Rapid fragment exploration
Parallel synthesis
Lead optimization
Candidate preparation & scale-up
Chemistry Capabilities
Small molecule Drug Discovery Expertise
- Extensive chemistry expertise to design and synthesize molecules for biological target activity
- Chemistry as our most powerful tool for generating novel IP and fine-tuning potency, phys-chem and ADME properties, toxicology alert-free fragments
Hit To Lead
- Experience-based design
- In-house fragment collections
- Parallel Synthesis
Chemistry-driven Lead Optimization
- Customized key fragments
- Ad hoc synthetic design and execution
Candidate Selection
- Scale-up of pre-clinical studies
- Route scouting and chemistry for GMP manufacture transfer
Electrophysiology Capabilities
Fully Customized. Mechanism-Driven.
No Stock Assays. No One-Size-Fits-All Protocols
At our company, electrophysiology is a core discovery capability, not a standardized service. We design program specific electrophysiological platforms tailored to the specific requirements of each drug-discovery program
Each target presents distinct gating behavior, regulation, and pharmacology
Each discovery program asks different mechanistic questions
Each decision point requires data aligned with biological reality
CELLULAR ELECTROPHYSIOLOGY
- Patch-clamp (manual & automated)
- Voltage-clamp and current-clamp protocols
- Assays for ion channels, transporters, and excitable cells
- Transfected, primary, engineered cellular models, ex vivo preparations
- Medium-throughput automated electrophysiology
ORGANELLAR ELECTROPHYSIOLOGY
- Lysosomal ion channel recordings
- Mitochondrial ion channel recordings
- Organelle-specific pharmacology
Tailored Electrophysiological Platforms
We develop program-specific assays designed to capture function, mechanism, and pharmacological modulation
- Target-specific assay design for ion channels, transporters, and excitable cell
- Optimization based on kinetics, gating properties, and mechanism of action
- Precise control of experimental parameters
- Temperature
- Ionic composition
- Stimulation and recording paradigms
- Custom data-analysis workflows aligned with project-critical endpoints
Advanced Lysosomal Research Platform
We combine native target electrophysiology with cellular readouts of lysosomal function to deliver an integrated biological assessment
These assays confirm pharmacology, define target biology, and support lead optimization and biomarker development
Where native ion-channel recordings meet high-content cellular biology
- Electrophysiology on isolated lysosomes (Lysopatch)
- Cellular markers to assess target impact on signalling and lysosomal regulation
- Lysosomal pH
- Autophagy
- Exocytosis
- α Synuclein aggregation and clearance
- Real-time live-cell imaging